Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905193 | 0.93 | MAPT (0.35) | HTTRAB9ANR1H4TP53MDM2 | |
| SCHEMBL19924427 | 0.89 | HTT (0.33) | HTTRAB9AKITPDGFRANR1H4 | |
| SCHEMBL25021283 | 0.86 | ALDH1A1 (0.33) | KITPDGFRAMAPK1 | |
| SCHEMBL21339315 | 0.86 | ALDH1A1 (0.33) | KITPDGFRAMAPK1 | |
| SCHEMBL17905149 | 0.86 | XBP1 (0.35) | RAB9ATP53MAPT | |
| SCHEMBL19910879 | 0.85 | HTT (0.33) | HTTRAB9APDGFRAMAPTMAPK1 | |
| SCHEMBL17905201 | 0.85 | MAPT (0.33) | RAB9APDGFRAMAPT | |
| SCHEMBL17896230 | 0.85 | HTT (0.35) | HTTMAPK1 | |
| SCHEMBL17905144 | 0.85 | MAPT (0.33) | HTTRAB9ATP53MDM2MAPT | |
| SCHEMBL17905159 | 0.85 | HTT (0.35) | HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231452-B2 | Thiopicolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-03-19 | — | — | US | disclosed |
| US-10172358-B2 | Thiopicolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180055051-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180055052-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | TST, TPMT, CYP51A1 | HTT 2375/4885RAB9A 2323/4885KIT 4761/4885 |
| US-10172358-B2 | Thiopicolinamide compounds with fungicidal activity | TST, TPMT, CYP51A1 | HTT 2465/4885RAB9A 2274/4885KIT 4825/4885 |
| US-10231452-B2 | Thiopicolinamide compounds with fungicidal activity | TST, TPMT, CYP51A1 | HTT 2375/4885RAB9A 2323/4885KIT 4761/4885 |
| US-20180055051-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | TST, TPMT, CYP51A1 | HTT 2465/4885RAB9A 2274/4885KIT 4825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.