Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905093 | 0.92 | RAB9A (0.35) | HTTRAB9ANR1H4TP53MDM2 | |
| SCHEMBL19910872 | 0.92 | NR3C1 (0.32) | RAB9ATP53PDGFRAKDRALDH1A1 | |
| SCHEMBL19910907 | 0.89 | HTT (0.31) | HTTRAB9ANR1H4TP53MDM2 | |
| SCHEMBL25022987 | 0.85 | ALDH1A1 (0.35) | PDGFRAALDH1A1SMN1; SMN2LMNAKIT | |
| SCHEMBL21339079 | 0.85 | ALDH1A1 (0.35) | PDGFRAALDH1A1SMN1; SMN2LMNAKIT | |
| SCHEMBL17904775 | 0.85 | NR3C1 (0.34) | RAB9ATP53PDGFRAKDRALDH1A1 | |
| SCHEMBL19910852 | 0.84 | HTT (0.35) | HTTRAB9ATP53MDM2PDGFRA | |
| SCHEMBL17905151 | 0.84 | SMN1; SMN2 (0.33) | RAB9APDGFRAKDRALDH1A1SMN1; SMN2 | |
| SCHEMBL17904858 | 0.84 | ALDH1A1 (0.36) | HTTRAB9AKDRALDH1A1SMN1; SMN2 | |
| SCHEMBL17896206 | 0.84 | HTT (0.37) | HTTTP53KDRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10172358-B2 | Thiopicolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| WO-2018044987-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-08 | — | — | WO | disclosed |
| WO-2018044991-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-08 | — | — | WO | disclosed |
| US-20180055051-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10172358-B2 | Thiopicolinamide compounds with fungicidal activity | TST, TPMT, CYP51A1 | HTT 2465/4885RAB9A 2274/4885NR1H4 2506/4885 |
| US-20180055051-A1 | THIOPICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | TST, TPMT, CYP51A1 | HTT 2465/4885RAB9A 2274/4885NR1H4 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.