SCHEMBL19913102

SCHEMBL19913102

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cc(C#N)c(-n2c3ccc(C(F)(F)F)cc3c3cc(C(F)(F)F)ccc32)cc1-c1ccncc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.36
XDH P47989 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
PIK3CG P48736 1/20 0.35
HTR6 P50406 3/20 0.35
HRH1 P35367 2/20 0.35
PTGDR2 Q9Y5Y4 2/20 0.35
LMNA P02545 3/20 0.34
KDM4E B2RXH2 2/20 0.34
TSHR P16473 2/20 0.34
PDE5A O76074 1/20 0.34
HPGD P15428 1/20 0.34
PTGS1 P23219 1/20 0.34
PDE4A P27815 1/20 0.34
CYP2C19 P33261 1/20 0.34
BLM P54132 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19913101 0.96 KDM4E (0.36) KIF11XDHPIK3CAPIK3CBPIK3CG
SCHEMBL19919621 0.94 KIF11 (0.38) KIF11XDHHTR6HRH1LMNA
SCHEMBL19908935 0.90 PDE3B (0.40) XDHHTR6HRH1PTGDR2LMNA
SCHEMBL19913104 0.90 XDH (0.35) KIF11XDHLMNAKDM4ETSHR
SCHEMBL19909072 0.90 ABCG2 (0.36) KIF11HTR6HRH1SCN9AMETAP2
SCHEMBL19913120 0.87 AR (0.35) XDHPDE3BPDE3AMEN1KMT2A
SCHEMBL19912425 0.87 KIF11 (0.36) KIF11XDHPIK3CAPIK3CBPIK3CG
SCHEMBL26777281 0.86 KIF11 (0.39) KIF11XDHPIK3CAPIK3CBPIK3CG
SCHEMBL19908934 0.86 ALDH1A1 (0.43) XDHHTR6HRH1PTGDR2LMNA
SCHEMBL19909058 0.86 KIF11 (0.38) KIF11XDHLMNAKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed