Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.35 |
| ▸ | MAT2A | P31153 | 5/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22170314 | 0.95 | KIF11 (0.38) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19913303 | 0.95 | KIF11 (0.42) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19909195 | 0.90 | KIF11 (0.45) | POLBKIF11MAT2AMETAP2GRM5 | |
| SCHEMBL19909130 | 0.89 | AURKA (0.34) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19913184 | 0.88 | KIF11 (0.38) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19912525 | 0.88 | KIF11 (0.36) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL22563511 | 0.86 | KIF11 (0.36) | POLBSMN1; SMN2KIF11MAT2AGRM5 | |
| SCHEMBL19903646 | 0.86 | POLB (0.36) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19909231 | 0.85 | METAP2 (0.40) | POLBLMNAHTTNCOA1SMN1; SMN2 | |
| SCHEMBL19913301 | 0.85 | ALDH1A1 (0.38) | LMNAHTTSMN1; SMN2KIF11METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180062085-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-03-01 | — | — | US | disclosed |