Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 5/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990158 | 0.91 | HRH4 (0.49) | HRH4TNKSPARP1TNKS2PRKCB | |
| SCHEMBL1991125 | 0.87 | HRH4 (0.55) | HRH4TNKSPARP1TNKS2PRKCB | |
| SCHEMBL1993947 | 0.81 | PRKCB (0.45) | HRH4PRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL12563577 | 0.81 | MCHR1 (0.46) | HRH4TNKSPARP1TNKS2HTR3A | |
| SCHEMBL1990872 | 0.80 | TRPV4 (0.45) | HRH4PRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL1994914 | 0.78 | HRH4 (0.46) | HRH4SCN9AHTR3AKDM4EHSD17B10 | |
| SCHEMBL1993409 | 0.78 | HRH4 (0.50) | HRH4PRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL1994108 | 0.77 | TLR9 (0.42) | HRH4PRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL1991112 | 0.77 | HRH4 (0.65) | HRH4HTR3AKDM4EUSP2ALDH1A1 | |
| SCHEMBL1993141 | 0.75 | HRH4 (0.56) | HRH4KDM4EHSD17B10MAPTCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | HRH4 249/4885TNKS 1393/4885PARP1 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.