Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 4/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990158 | 0.91 | HRH4 (0.49) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL1990872 | 0.87 | TRPV4 (0.45) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL1994108 | 0.84 | TLR9 (0.42) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL1993681 | 0.83 | HRH4 (0.61) | HRH4HTR3AALDH1A1KDM4EGLA | |
| SCHEMBL1991360 | 0.81 | HRH4 (0.51) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL1993409 | 0.81 | HRH4 (0.50) | PRKCBPRKCAPRKCHPRKCEPRKCQ | |
| SCHEMBL1995226 | 0.81 | LATS1 (0.45) | HRH4HTR6HTR3AALDH1A1KDM4E | |
| SCHEMBL1991112 | 0.80 | HRH4 (0.65) | HRH4HTR3AALDH1A1KDM4E | |
| SCHEMBL1989930 | 0.78 | HTR3A (0.45) | HRH4CSF1RHTR3AALDH1A1L3MBTL1 | |
| SCHEMBL1998966 | 0.78 | EHMT1 (0.51) | HRH4HTR6HTR3AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | PRKCB 3335/4885PRKCA 3438/4885PRKCH 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.