Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.30 |
| ▸ | TEK | Q02763 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19915591 | 0.84 | CYP17A1 (0.32) | ADK | |
| SCHEMBL19923341 | 0.81 | WNT3A (0.34) | — | |
| SCHEMBL19899679 | 0.72 | CYP19A1 (0.33) | — | |
| SCHEMBL19915623 | 0.70 | MITF (0.31) | KMT2ANPSR1 | |
| SCHEMBL19915693 | 0.65 | — | — | |
| SCHEMBL26794160 | 0.63 | CYP1A2 (0.52) | ADK | |
| SCHEMBL25544738 | 0.63 | CYP2A6 (0.34) | — | |
| SCHEMBL10259398 | 0.61 | NQO2 (0.47) | — | |
| SCHEMBL12313649 | 0.61 | CYP1A2 (0.42) | KMT2A | |
| SCHEMBL19899676 | 0.61 | TDP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | disclosed |