Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26260084 | 0.74 | HIF1A (0.44) | CYP19A1CYP11B1CYP11B2CYP17A1ERN1 | |
| SCHEMBL19915556 | 0.72 | ADK (0.33) | — | |
| SCHEMBL19915591 | 0.68 | CYP17A1 (0.32) | CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL3393106 | 0.63 | ATP1A1 (0.37) | PDE4BKDM4EALDH1A1 | |
| SCHEMBL30163883 | 0.63 | ATP1A1 (0.37) | PDE4BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL2111356 | 0.62 | PDE10A (0.38) | PDE4BKDM4EALDH1A1 | |
| SCHEMBL27278545 | 0.62 | AGXT (0.45) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9688862 | 0.60 | AGXT (0.44) | KDM4EALDH1A1 | |
| SCHEMBL10555560 | 0.60 | ACHE (0.43) | ERN1NPC1KDM4EALDH1A1 | |
| SCHEMBL26260037 | 0.59 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP17A1ERN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | disclosed |