Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19915556 | 0.84 | ADK (0.33) | ADK | |
| SCHEMBL19915693 | 0.78 | — | — | |
| SCHEMBL19923341 | 0.66 | WNT3A (0.34) | — | |
| SCHEMBL18425754 | 0.65 | NOS1 (0.33) | — | |
| SCHEMBL19899676 | 0.62 | TDP1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL22966311 | 0.61 | CSNK2A2 (0.39) | PDGFRBPDGFRACSNK2A2CSNK2B | |
| SCHEMBL3637489 | 0.60 | CYP2A6 (0.43) | PDGFRBPDGFRA | |
| SCHEMBL18464844 | 0.60 | POLB (0.42) | CYP3A4 | |
| SCHEMBL31263625 | 0.60 | NOS1 (0.40) | PDGFRBPDGFRA | |
| SCHEMBL6975325 | 0.59 | CRHR1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | disclosed |