SCHEMBL19917825

SCHEMBL19917825

CC(C)(C)[C@H]1OCC[C@@H]1OP(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
INPP5A Q14642 3/20 0.38
ITPR2 Q14571 1/20 0.33
ITPR3 Q14573 1/20 0.33
ITPR1 Q14643 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29167358 0.72
SCHEMBL432511 0.69 INPP5A (0.39) INPP5AITPR2ITPR3ITPR1
SCHEMBL10023962 0.69 INPP5A (0.39) INPP5AITPR2ITPR3ITPR1
SCHEMBL19464721 0.69 INPP5A (0.39) INPP5AITPR2ITPR3ITPR1
SCHEMBL15492995 0.69 INPP5A (0.39) INPP5AITPR2ITPR3ITPR1
SCHEMBL481700 0.69 INPP5A (0.39) INPP5AITPR2ITPR3ITPR1
SCHEMBL14930895 0.67 FBP1 (0.46) INPP5A
SCHEMBL22946277 0.65 SMN1; SMN2 (0.37) INPP5A
SCHEMBL6690286 0.63 INPP5A (0.35) INPP5AITPR2ITPR3ITPR1
SCHEMBL14408100 0.62 INPP5A (0.58) INPP5AITPR2ITPR3ITPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317521-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2021-10-14 US disclosed
US-11008613-B2 Tagged nucleotides useful for nanopore detection Roche Sequencing Solutions, Inc. (US) 2021-05-18 US disclosed
US-20200216894-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2020-07-09 US disclosed
US-10669580-B2 Tagged nucleotides useful for nanopore detection Roche Sequencing Solutions, Inc. (US) 2020-06-02 US disclosed
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION Roche Sequencing Solutions, Inc. 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10669580-B2 Tagged nucleotides useful for nanopore detection PHAX, POLRMT, POLN INPP5A 726/4885ITPR2 896/4885ITPR3 1268/4885
US-20180057870-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN INPP5A 726/4885ITPR2 896/4885ITPR3 1268/4885
US-20200216894-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN INPP5A 726/4885ITPR2 896/4885ITPR3 1268/4885
US-20210317521-A1 TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION PHAX, POLRMT, POLN INPP5A 726/4885ITPR2 896/4885ITPR3 1268/4885
US-11008613-B2 Tagged nucleotides useful for nanopore detection PHAX, POLRMT, POLN INPP5A 726/4885ITPR2 896/4885ITPR3 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.