Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | PTPRB | P23467 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17345002 | 0.89 | TSHR (0.58) | TSHRAKR1C3CETPPDPK1MTOR | |
| SCHEMBL8384625 | 0.83 | TSHR (0.52) | TSHRAKR1C3CETPPTPN1MEN1 | |
| SCHEMBL28365963 | 0.81 | TSHR (0.50) | TSHRAKR1C3CETPPDPK1MTOR | |
| SCHEMBL4906498 | 0.79 | TSHR (0.48) | TSHRAKR1C3CETPPDPK1MTOR | |
| SCHEMBL31091007 | 0.79 | TSHR (0.48) | TSHRAKR1C3S1PR1S1PR3PTPN2 | |
| SCHEMBL12786033 | 0.79 | TSHR (0.48) | TSHRAKR1C3S1PR1S1PR3 | |
| SCHEMBL27541457 | 0.79 | TSHR (0.48) | TSHRAKR1C3MEN1KMT2A | |
| SCHEMBL207268 | 0.79 | RAB9A (0.53) | TSHRAKR1C3S1PR1S1PR3 | |
| SCHEMBL9093550 | 0.79 | FDPS (0.50) | TSHRAKR1C3CETPS1PR1S1PR3 | |
| SCHEMBL206610 | 0.78 | TSHR (0.76) | TSHRCETPPDPK1MTORFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669580-B2 | Tagged nucleotides useful for nanopore detection | Roche Sequencing Solutions, Inc. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | Roche Sequencing Solutions, Inc. | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10669580-B2 | Tagged nucleotides useful for nanopore detection | PHAX, POLRMT, POLN | TSHR 3880/4885AKR1C3 4256/4885CETP 4098/4885 |
| US-20180057870-A1 | TAGGED NUCLEOTIDES USEFUL FOR NANOPORE DETECTION | PHAX, POLRMT, POLN | TSHR 3880/4885AKR1C3 4256/4885CETP 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.