Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 6/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559219 | 0.65 | TAAR1 (0.46) | SOD1PDPK1MAPTKDM4EGAA | |
| SCHEMBL14540067 | 0.64 | — | — | |
| SCHEMBL30045340 | 0.61 | IDO1 (0.36) | — | |
| SCHEMBL17435989 | 0.59 | SOD1 (0.47) | SOD1PDPK1DAOCYP2C19 | |
| SCHEMBL20159291 | 0.59 | FERMT2 (0.40) | MAPTGAA | |
| SCHEMBL18739206 | 0.59 | KCNH3 (0.39) | MAPTKDM4EGAACYP2C19 | |
| SCHEMBL6231601 | 0.59 | TRPA1 (0.41) | — | |
| SCHEMBL11935799 | 0.58 | PRSS1 (0.36) | LMNA | |
| SCHEMBL12297780 | 0.58 | SOD1 (0.44) | SOD1PDPK1MAPTKDM4ELMNA | |
| SCHEMBL17435992 | 0.58 | SOD1 (0.45) | SOD1PDPK1MAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367798-B1 | PYRAZOLONE DERIVATIVES USEFUL IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS | UNIV NORTHWESTERN (US) | 2018-02-28 | — | — | EP | disclosed |