SCHEMBL19918680

SCHEMBL19918680

c1ccc(-c2nc(-n3c4ccccc4c4cc(-c5ccc6oc7cc8c9c(cccc9c7c6c5)-c5ccccc5-8)ccc43)nc3c2ccc2ccccc23)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918681 0.99 PIM1 (0.30)
SCHEMBL19918548 0.89 MAPK1 (0.32) MAPK1KMT2A
SCHEMBL19918677 0.88 ALDH1A1 (0.37) MAPK1KMT2A
SCHEMBL19918558 0.88 MAPK1 (0.31) MAPK1KMT2A
SCHEMBL19918682 0.88 PTGES (0.35)
SCHEMBL19918683 0.88 ALDH1A1 (0.37) MAPK1KMT2A
SCHEMBL20821738 0.87 SIRT2 (0.34)
SCHEMBL19918679 0.87 ALDH1A1 (0.33) MAPK1KMT2A
SCHEMBL19918678 0.86 ALDH1A1 (0.32) MAPK1
SCHEMBL19918715 0.84 TSPO (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed