SCHEMBL19918683

SCHEMBL19918683

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5cc(-c6ccc7oc8cc9c%10c(cccc%10c8c7c6)-c6ccccc6-9)ccc54)nc4ccccc34)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 4/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPY5R Q15761 1/20 0.32
TSPO P30536 1/20 0.31
GAA P10253 2/20 0.31
KMT2A Q03164 2/20 0.31
NUDT1 P36639 2/20 0.31
MEN1 O00255 1/20 0.31
PRKDC P78527 1/20 0.31
ADORA2A P29274 2/20 0.30
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918677 0.99 ALDH1A1 (0.37) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19918678 0.95 ALDH1A1 (0.32) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19918679 0.94 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19918682 0.89 PTGES (0.35) ALDH1A1HPGDKDM4EMAPTPIK3CD
SCHEMBL19918681 0.89 PIM1 (0.30) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL19918534 0.89 TSPO (0.33) ALDH1A1HPGDL3MBTL1MAPK1TSPO
SCHEMBL19918481 0.88 KDM4E (0.31) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL19918680 0.88 MAPK1 (0.30) MAPK1KMT2A
SCHEMBL19918573 0.88 PLA2G2A (0.32) ALDH1A1HPGDKDM4EMAPTL3MBTL1
SCHEMBL16475761 0.87 L3MBTL1 (0.35) ALDH1A1HPGDKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038400-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING SAME 주식회사 두산 2018-03-01 WO disclosed