SCHEMBL19919645

SCHEMBL19919645

Cc1cc(-c2cc(-n3c4cc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)ccc4c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc43)c(C#N)cc2-n2c3cc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)ccc3c3ccc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc32)cc(C)n1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.36
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CTSS P25774 2/20 0.33
CTSK P43235 2/20 0.33
AR P10275 3/20 0.33
GRM2 Q14416 3/20 0.32
XDH P47989 2/20 0.32
RXRA P19793 2/20 0.32
RXRB P28702 1/20 0.32
PSEN1 P49768 2/20 0.31
PSEN2 P49810 2/20 0.31
APH1B Q8WW43 2/20 0.31
NCSTN Q92542 2/20 0.31
APH1A Q96BI3 2/20 0.31
PSENEN Q9NZ42 2/20 0.31
EIF4EBP1 Q13541 2/20 0.31
RXRG P48443 1/20 0.31
PIK3R2 O00459 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919643 0.96 METAP2 (0.34) METAP2CYP11B1CYP11B2CTSSCTSK
SCHEMBL19913252 0.96 METAP2 (0.34) METAP2CYP11B1CYP11B2CTSSCTSK
SCHEMBL19917927 0.92 CYP11B1 (0.36) CYP11B1CYP11B2CTSSCTSKAR
SCHEMBL19919652 0.92 CYP11B1 (0.34) CYP11B1CYP11B2CTSSCTSKAR
SCHEMBL19913254 0.92 AR (0.34) METAP2CYP11B1CYP11B2ARXDH
SCHEMBL23487634 0.91 CYP11B1 (0.34) METAP2CYP11B1CYP11B2CTSSCTSK
SCHEMBL21440706 0.91 AR (0.36) CYP11B1CYP11B2CTSSCTSKAR
SCHEMBL22170304 0.90 XDH (0.34) METAP2CYP11B1CYP11B2ARGRM2
SCHEMBL19917915 0.89 AR (0.44) CYP11B1CYP11B2CTSSCTSKAR
SCHEMBL19912450 0.89 AR (0.37) CYP11B1CYP11B2CTSSCTSKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 METAP2 3353/4885CYP11B1 1400/4885CYP11B2 965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.