SCHEMBL19923656

SCHEMBL19923656

CCC1(c2ccccc2)C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.39
MITF O75030 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 2/20 0.35
CYP2C19 P33261 4/20 0.35
TSHR P16473 1/20 0.35
ALDH1A1 P00352 1/20 0.33
BACE1 P56817 1/20 0.33
BACE2 Q9Y5Z0 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923541 0.86 ELANE (0.39) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923633 0.86 ELANE (0.41) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923689 0.85 ELANE (0.40) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923659 0.83 KMT2A (0.40) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923578 0.83 MITF (0.40) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923587 0.82 MITF (0.39) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923711 0.82 ELANE (0.41) ELANELMNACYP2C19TSHRALDH1A1
SCHEMBL19923429 0.81 MITF (0.39) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923408 0.79 NPSR1 (0.43) ELANEMITFMEN1KMT2ALMNA
SCHEMBL19923662 0.79 ALDH1A1 (0.39) ELANEMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ELANE 1249/4885MITF 4251/4885MEN1 2213/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ELANE 1276/4885MITF 4361/4885MEN1 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.