SCHEMBL19923705

SCHEMBL19923705

CC[Si](CC)(CC)N1C(=O)N([Si](CC)(CC)CC)C(C)(c2ccccc2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
BACE1 P56817 3/20 0.37
BACE2 Q9Y5Z0 2/20 0.37
LMNA P02545 2/20 0.36
CYP2C19 P33261 3/20 0.36
TSHR P16473 2/20 0.36
TP53 P04637 1/20 0.34
ELANE P08246 2/20 0.33
REN P00797 1/20 0.33
APP P05067 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTR1A P08908 1/20 0.33
HTR6 P50406 1/20 0.33
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923549 0.86 TSHR (0.38) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923502 0.85 BACE1 (0.38) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923573 0.84 HTR1A (0.43) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923551 0.84 BACE1 (0.37) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923646 0.84 ALDH1A1 (0.35) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923574 0.84 ELANE (0.37) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923536 0.82 ELANE (0.49) ALDH1A1BACE1BACE2LMNAELANE
SCHEMBL19923418 0.82 KMT2A (0.41) ALDH1A1BACE1BACE2LMNACYP2C19
SCHEMBL19923691 0.81 CYP2C19 (0.42) ALDH1A1LMNACYP2C19ELANEGAA
SCHEMBL19923706 0.78 ALDH1A1 (0.39) ALDH1A1BACE1BACE2LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN ALDH1A1 2648/4885BACE1 4315/4885BACE2 4642/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM ALDH1A1 2554/4885BACE1 4432/4885BACE2 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.