SCHEMBL19923709

SCHEMBL19923709

CCC1(CC)C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.40
ELANE P08246 7/20 0.38
ALDH1A1 P00352 2/20 0.34
LMNA P02545 3/20 0.33
CYP2C19 P33261 4/20 0.33
TSHR P16473 1/20 0.33
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923748 0.84 NPSR1 (0.40) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923772 0.83 NPSR1 (0.39) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923711 0.82 ELANE (0.41) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923771 0.82 NPSR1 (0.38) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923659 0.81 KMT2A (0.40) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923693 0.80 NPSR1 (0.49) NPSR1ELANEALDH1A1LMNACYP2C19
SCHEMBL19923515 0.79 ALDH1A1 (0.37) ELANEALDH1A1
SCHEMBL19923448 0.76 NPSR1 (0.52) NPSR1ELANECYP2C19TSHR
SCHEMBL19923548 0.76 ALDH1A1 (0.36) NPSR1ALDH1A1LMNATSHRBACE1
SCHEMBL19923514 0.75 ALDH1A1 (0.41) ELANEALDH1A1LMNABACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN NPSR1 1322/4885ELANE 1249/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM NPSR1 1281/4885ELANE 1276/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.