SCHEMBL19923748

SCHEMBL19923748

CCC1(CC)C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.40
ELANE P08246 6/20 0.38
CYP2C19 P33261 4/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.35
ALDH1A1 P00352 1/20 0.34
PLA2G7 Q13093 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.32
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923771 0.85 NPSR1 (0.38) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923709 0.84 NPSR1 (0.40) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923772 0.83 NPSR1 (0.39) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923711 0.82 ELANE (0.41) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923578 0.81 MITF (0.40) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923693 0.80 NPSR1 (0.49) NPSR1ELANECYP2C19TSHRLMNA
SCHEMBL19923638 0.79 PLA2G7 (0.45) ELANELMNAALDH1A1PLA2G7L3MBTL1
SCHEMBL19923464 0.76 PKM (0.39) CYP2C19TSHRLMNAALDH1A1L3MBTL1
SCHEMBL19923548 0.76 ALDH1A1 (0.36) NPSR1TSHRLMNAALDH1A1BACE1
SCHEMBL19923472 0.75 ALDH1A1 (0.41) CYP2C19TSHRLMNAALDH1A1PLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN NPSR1 1322/4885ELANE 1249/4885CYP2C19 1347/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM NPSR1 1281/4885ELANE 1276/4885CYP2C19 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.