Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.53 |
| ▸ | EP300 | Q09472 | 2/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | CMA1 | P23946 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923642 | 0.80 | EHMT2 (0.49) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL19923759 | 0.80 | SMO (0.60) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL19923710 | 0.79 | EHMT2 (0.47) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL19923469 | 0.78 | EHMT2 (0.46) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL19923475 | 0.78 | EHMT2 (0.46) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL13792821 | 0.77 | MEN1 (0.61) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL19923664 | 0.75 | EHMT2 (0.54) | HDAC6EHMT2EP300ELANEF2 | |
| SCHEMBL11259949 | 0.75 | HDAC6 (0.62) | HDAC6EP300HDAC1HDAC2HDAC8 | |
| SCHEMBL11264078 | 0.74 | HDAC6 (0.74) | HDAC6EP300ELANEF2PLG | |
| SCHEMBL17358741 | 0.74 | ELANE (0.67) | EHMT2EP300ELANEF2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | claimed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | claimed |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | disclosed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | PARG, HNMT, PARN | HDAC6 117/4885EHMT2 54/4885EP300 1191/4885 |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | HNMT, PARG, PAM | HDAC6 151/4885EHMT2 53/4885EP300 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.