SCHEMBL19923710

SCHEMBL19923710

CCC1C(=O)N([Si](CC)(CC)CC)C(=O)N1Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.47
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
SMO Q99835 2/20 0.40
F2 P00734 1/20 0.39
PLG P00747 1/20 0.39
ELANE P08246 1/20 0.39
CTSG P08311 1/20 0.39
CMA1 P23946 1/20 0.39
CTRC Q99895 1/20 0.39
BRD4 O60885 2/20 0.38
EP300 Q09472 1/20 0.38
HDAC6 Q9UBN7 3/20 0.38
IDO1 P14902 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923475 0.90 EHMT2 (0.46) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923642 0.87 EHMT2 (0.49) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923469 0.84 EHMT2 (0.46) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923622 0.84 SMO (0.53) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923492 0.82 EHMT2 (0.46) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923714 0.79 HDAC6 (0.55) EHMT2MEN1KMT2AF2PLG
SCHEMBL19923682 0.78 L3MBTL1 (0.33)
SCHEMBL19923478 0.77 CYP1A2 (0.39) MEN1KMT2AMAPTMAPK1ELANE
SCHEMBL19923607 0.74 SMO (0.52) EHMT2MEN1KMT2AMAPTTSHR
SCHEMBL19923417 0.72 EHMT2 (0.45) EHMT2MEN1KMT2AMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN EHMT2 54/4885MEN1 2213/4885KMT2A 1080/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM EHMT2 53/4885MEN1 2164/4885KMT2A 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.