SCHEMBL19923720

SCHEMBL19923720

CCC1(c2ccccc2)C(=O)N([Si](C)(C)C)C(=O)N1Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.44
ELANE P08246 5/20 0.43
CYP2C19 P33261 3/20 0.43
MITF O75030 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CTSG P08311 2/20 0.38
PRTN3 P24158 1/20 0.38
OPRM1 P35372 1/20 0.37
OPRL1 P41146 1/20 0.37
F2 P00734 1/20 0.37
PLG P00747 1/20 0.37
CMA1 P23946 1/20 0.37
CTRC Q99895 1/20 0.37
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923575 0.88 NPSR1 (0.43) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923565 0.87 MITF (0.41) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923742 0.87 NPSR1 (0.43) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923408 0.87 NPSR1 (0.43) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923621 0.82 NPSR1 (0.51) NPSR1ELANECYP2C19MEN1KMT2A
SCHEMBL19923487 0.82 ELANE (0.41) NPSR1ELANECYP2C19ALDH1A1CTSG
SCHEMBL19923755 0.82 NPSR1 (0.59) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923637 0.81 ELANE (0.44) NPSR1ELANECYP2C19ALDH1A1CTSG
SCHEMBL19923592 0.80 MITF (0.42) NPSR1ELANECYP2C19MITFMEN1
SCHEMBL19923402 0.80 KMT2A (0.42) NPSR1ELANECYP2C19MITFMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN NPSR1 1322/4885ELANE 1249/4885CYP2C19 1347/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM NPSR1 1281/4885ELANE 1276/4885CYP2C19 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.