SCHEMBL19923402

SCHEMBL19923402

CCC1(c2ccccc2)C(=O)N([Si](C)(C)C)C(=O)N1[Si](C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
MITF O75030 2/20 0.42
MEN1 O00255 2/20 0.42
LMNA P02545 3/20 0.38
CYP2C19 P33261 4/20 0.38
TSHR P16473 2/20 0.38
BACE1 P56817 1/20 0.36
BACE2 Q9Y5Z0 1/20 0.36
ELANE P08246 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923592 0.85 MITF (0.42) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923565 0.84 MITF (0.41) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923412 0.82 MITF (0.40) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923633 0.82 ELANE (0.41) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923692 0.82 ELANE (0.51) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923418 0.81 KMT2A (0.41) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923720 0.80 NPSR1 (0.44) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923659 0.79 KMT2A (0.40) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923672 0.79 KMT2A (0.40) KMT2AMITFMEN1LMNACYP2C19
SCHEMBL19923688 0.78 ALDH1A1 (0.37) LMNACYP2C19TSHRBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN KMT2A 1080/4885MITF 4251/4885MEN1 2213/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM KMT2A 999/4885MITF 4361/4885MEN1 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.