Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 10/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 6/20 | 0.40 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923514 | 0.84 | ALDH1A1 (0.41) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923559 | 0.84 | HTR1A (0.42) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923686 | 0.82 | ALDH1A1 (0.37) | ALDH1A1BACE1BACE2APPREN | |
| SCHEMBL19923558 | 0.82 | ELANE (0.41) | HTR1AHTR6ALDH1A1GAA | |
| SCHEMBL19923573 | 0.81 | HTR1A (0.43) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923700 | 0.80 | HTR1A (0.40) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923652 | 0.77 | TSHR (0.38) | ALDH1A1BACE1BACE2APPREN | |
| SCHEMBL19923740 | 0.76 | HTR1A (0.46) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923472 | 0.75 | ALDH1A1 (0.41) | HTR1AHTR6ALDH1A1BACE1BACE2 | |
| SCHEMBL19923706 | 0.71 | ALDH1A1 (0.39) | HTR1AHTR6ALDH1A1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | claimed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | claimed |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | BRIDGESTONE CORPORATION (JP) | 2021-01-26 | — | — | US | disclosed |
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065935-A1 | POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS | PARG, HNMT, PARN | HTR1A 456/4885HTR6 77/4885ALDH1A1 2648/4885 |
| US-10899718-B2 | Polymers functionalized with N-protected hydantoin compounds | HNMT, PARG, PAM | HTR1A 341/4885HTR6 77/4885ALDH1A1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.