Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990746 | 0.88 | RECQL (0.52) | RECQLALDH1A1SMN1; SMN2OPRM1SLC6A4 | |
| SCHEMBL1991871 | 0.82 | L3MBTL1 (0.48) | RECQLALDH1A1SMN1; SMN2L3MBTL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL1992026 | 0.79 | RECQL (0.52) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL1994342 | 0.78 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL5323230 | 0.73 | SMN1; SMN2 (0.73) | RECQLALDH1A1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL1991515 | 0.73 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL1999644 | 0.73 | RECQL (0.47) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL1999648 | 0.73 | RECQL (0.47) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL1999645 | 0.73 | RECQL (0.47) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL14979187 | 0.72 | ALDH1A1 (0.64) | RECQLALDH1A1SMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | RECQL 3604/4885ALDH1A1 297/4885SMN1; SMN2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.