Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | DTYMK | P23919 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990746 | 0.86 | RECQL (0.52) | RECQLALDH1A1SMN1; SMN2SLC6A4HTR2A | |
| SCHEMBL1993899 | 0.83 | L3MBTL1 (0.48) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1992641 | 0.82 | RECQL (0.52) | L3MBTL1RECQLALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL1994908 | 0.80 | L3MBTL1 (0.50) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL2002226 | 0.79 | L3MBTL1 (0.50) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1991434 | 0.77 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1991437 | 0.77 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1996881 | 0.76 | L3MBTL1 (0.48) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL31323712 | 0.71 | CYP11B2 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2NPC1LMNA | |
| SCHEMBL1995091 | 0.71 | AKR1B1 (0.36) | SMN1; SMN2CNR2LMNAHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885RECQL 3604/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.