Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185483 | 0.92 | OPRL1 (0.38) | OPRL1CNR2BTKFAAHPTK2 | |
| SCHEMBL186275 | 0.91 | BTK (0.38) | OPRL1CNR2BTKFAAHPTK2 | |
| SCHEMBL185517 | 0.91 | OPRL1 (0.37) | OPRL1CNR2BTKFAAHPTGES | |
| SCHEMBL186511 | 0.89 | OPRL1 (0.39) | OPRL1CNR2BTKFAAHPTK2 | |
| SCHEMBL2807467 | 0.89 | OPRL1 (0.38) | OPRL1CNR2PTK2BDKRB1 | |
| SCHEMBL185881 | 0.89 | OPRL1 (0.37) | OPRL1CNR2BTKFAAHTRPV1 | |
| SCHEMBL14856844 | 0.85 | METAP2 (0.38) | OPRL1CNR2 | |
| SCHEMBL14856577 | 0.85 | FAAH (0.34) | CNR2FAAHTRPV1BDKRB1 | |
| SCHEMBL185518 | 0.85 | OPRL1 (0.37) | OPRL1CNR2FAAHTRPV1 | |
| SCHEMBL14856521 | 0.85 | OPRL1 (0.33) | OPRL1CNR2BTKFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010097372-A1 | COMPOUNDS AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |