Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928558 | 0.91 | MAPT (0.35) | MAPTCA1BTN3A1CYP2C19TRPA1 | |
| SCHEMBL21727779 | 0.85 | MAPT (0.34) | MAPTCA1BTN3A1CYP2C19TRPA1 | |
| SCHEMBL19928533 | 0.85 | MAPT (0.33) | MAPTCA1BTN3A1CYP2C19 | |
| SCHEMBL19928534 | 0.83 | MAPT (0.36) | MAPTCA1BTN3A1CYP2C19KMT2A | |
| SCHEMBL15892778 | 0.82 | MAPT (0.37) | MAPTCA1BTN3A1CYP2C19PRKCA | |
| SCHEMBL14747381 | 0.81 | CA1 (0.41) | MAPTCA1CYP2C19HTTKMT2A | |
| SCHEMBL19928559 | 0.81 | MAPT (0.33) | MAPTCA1BTN3A1CYP2C19KMT2A | |
| SCHEMBL8554241 | 0.81 | PRKCA (0.36) | MAPTCA1BTN3A1CYP2C19TRPA1 | |
| SCHEMBL19928527 | 0.81 | MAPT (0.32) | MAPTCA1KMT2A | |
| SCHEMBL7159471 | 0.80 | SLC1A3 (0.43) | MAPTCA1CYP2C19TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9907854-B2 | Crosslinking reagents, macromolecules, therapeutic bioconjugates, and synthetic methods thereof | CellMosaic, Inc. (US) | 2018-03-06 | — | — | US | disclosed |