SCHEMBL19928644

SCHEMBL19928644

COC[C@H]1OC(n2cc(C)c(=O)[nH]c2=O)CC1O[PH](=O)O

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.57
RNASE1 P07998 1/20 0.52
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15448880 0.89 TK1 (0.57) TK1RNASE1
SCHEMBL14867212 0.89 TK1 (0.57) TK1RNASE1
SCHEMBL17122961 0.89 LMNA (0.54) TK1
SCHEMBL15236309 0.87 TK1 (0.59) TK1RNASE1
SCHEMBL12360859 0.87 TK1 (0.59) TK1RNASE1
SCHEMBL16426201 0.87 TK1 (0.59) TK1RNASE1
SCHEMBL7243145 0.84 TK1 (0.62) TK1RNASE1POLB
SCHEMBL135209 0.82 TK1 (0.69) TK1POLB
SCHEMBL17232081 0.82 TK1 (0.69) TK1POLB
SCHEMBL22943603 0.82 TK1 (0.69) TK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9909177-B2 Pyrosequencing methods and related compositions THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-03-06 US disclosed