Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177694 | 0.84 | L3MBTL1 (0.37) | KMT2AMEN1LMNAHTTL3MBTL1 | |
| SCHEMBL24713588 | 0.81 | KDM4E (0.42) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22550677 | 0.81 | KDM4E (0.42) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL178285 | 0.81 | KDM4E (0.42) | L3MBTL1KDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1160925 | 0.77 | KMT2A (0.51) | KMT2AL3MBTL1KDM4ERAD52HRH3 | |
| SCHEMBL24745758 | 0.76 | SMN1; SMN2 (0.49) | KMT2AL3MBTL1KDM4ERAD52HRH3 | |
| SCHEMBL19928708 | 0.74 | SIGMAR1 (0.46) | L3MBTL1KDM4EALDH1A1TSHR | |
| SCHEMBL25821066 | 0.74 | ALDH1A1 (0.35) | KMT2AMEN1LMNAHTTL3MBTL1 | |
| SCHEMBL23269619 | 0.74 | KMT2A (0.51) | KMT2AL3MBTL1KDM4ERAD52L3MBTL3 | |
| SCHEMBL8326704 | 0.74 | SIGMAR1 (0.47) | KMT2AMEN1LMNAHRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908872-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-03-06 | — | — | US | disclosed |