Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 8/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | KLK8 | O60259 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | KLK2 | P20151 | 1/20 | 0.31 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19470239 | 0.83 | FGFR1 (0.53) | FGFR1SLC22A6EP300TLR7 | |
| SCHEMBL19470252 | 0.83 | FGFR1 (0.49) | FGFR1SLC22A6EP300TLR7 | |
| SCHEMBL19929315 | 0.79 | DUT (0.44) | — | |
| SCHEMBL4711405 | 0.76 | FGFR1 (0.58) | FGFR1SLC22A6EP300 | |
| SCHEMBL30364353 | 0.75 | FGFR1 (0.46) | FGFR1SLC22A6EP300 | |
| SCHEMBL19929316 | 0.74 | SLC22A6 (0.45) | FGFR1SLC22A6 | |
| SCHEMBL17622587 | 0.74 | POLB (0.60) | — | |
| SCHEMBL19470310 | 0.74 | FGFR1 (0.50) | FGFR1SLC22A6EP300TLR7 | |
| SCHEMBL19929313 | 0.73 | FGFR1 (0.62) | FGFR1SLC22A6 | |
| SCHEMBL19470297 | 0.73 | FGFR1 (0.53) | FGFR1SLC22A6TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | UNIV CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | FGFR1 3394/4885SLC22A6 1764/4885BTN3A1 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.