Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | XDH | P47989 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.50 |
| ▸ | POLH | Q9Y253 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934849 | 0.90 | CYP3A4 (0.50) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929836 | 0.88 | CYP3A4 (0.57) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29732709 | 0.88 | CYP3A4 (0.57) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929831 | 0.86 | MEN1 (0.51) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929829 | 0.82 | MEN1 (0.64) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929822 | 0.82 | MEN1 (0.45) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929827 | 0.82 | KDM4E (0.51) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19934851 | 0.82 | KDM4E (0.51) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929846 | 0.80 | LCK (0.49) | CYP3A4MEN1KMT2AMAPTKDM4E | |
| SCHEMBL19929824 | 0.76 | APP (0.56) | CYP3A4MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-12-17 | — | — | US | disclosed |
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2018-03-08 | — | — | US | disclosed |
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HPGDS, DPP7, DPEP1 | CYP3A4 717/4885MEN1 157/4885KMT2A 4047/4885 |
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | HPGDS, DPP7, DPEP1 | CYP3A4 717/4885MEN1 157/4885KMT2A 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.