Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | XDH | P47989 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.51 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929827 | 0.94 | KDM4E (0.51) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929830 | 0.92 | MIF (0.46) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929831 | 0.90 | MEN1 (0.51) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929836 | 0.85 | CYP3A4 (0.57) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL29732709 | 0.85 | CYP3A4 (0.57) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19934850 | 0.83 | CYP1A2 (0.47) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929835 | 0.82 | CYP3A4 (0.50) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19934849 | 0.82 | CYP3A4 (0.50) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929832 | 0.79 | CA12 (0.49) | KDM4ECYP3A4MEN1KMT2AMAPT | |
| SCHEMBL19929824 | 0.77 | APP (0.56) | KDM4ECYP3A4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-12-17 | — | — | US | disclosed |
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HPGDS, DPP7, DPEP1 | KDM4E 3016/4885CYP3A4 717/4885MEN1 157/4885 |
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | HPGDS, DPP7, DPEP1 | KDM4E 3016/4885CYP3A4 717/4885MEN1 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.