SCHEMBL19934675

SCHEMBL19934675

NC[C@@H](CS)NC[C@H](N)CS

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.38
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
ANPEP P15144 3/20 0.32
ENPEP Q07075 1/20 0.32
ERAP2 Q6P179 1/20 0.32
ERAP1 Q9NZ08 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21111319 1.00 OPRK1 (0.38) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL21153274 1.00 OPRK1 (0.38) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL21134687 1.00 OPRK1 (0.38) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL19934670 1.00 OPRK1 (0.38) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL19934633 1.00 OPRK1 (0.38) OPRK1FNTAFNTBANPEPENPEP
Hydrochloric Acid SCHEMBL21084949 0.98 OPRK1 (0.37) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL19934776 0.98 OPRK1 (0.37) OPRK1FNTAFNTBANPEPENPEP
Hydrochloric Acid SCHEMBL21084937 0.98 OPRK1 (0.37) OPRK1FNTAFNTBANPEPENPEP
SCHEMBL21153703 0.98 OPRK1 (0.37) OPRK1FNTAFNTBANPEPENPEP
Hydrochloric Acid SCHEMBL21084938 0.98 OPRK1 (0.37) OPRK1FNTAFNTBANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation SHANGHAI KECHOW PHARMA, INC (CN) 2021-05-18 US disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 EP disclosed
EP-3508476-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) 2019-07-10 EP disclosed
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA, INC. (CN) 2019-07-04 US disclosed
WO-2018041245-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION 中国医学科学院放射医学研究所 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202779-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION MGMT, PRMT8, SULT1A1 OPRK1 2230/4885FNTA 1954/4885FNTB 1874/4885
US-11008286-B2 Amino mercaptan compound and preparation method therefor and use thereof in protection against radiation MGMT, GSTA1, PRMT1 OPRK1 2184/4885FNTA 481/4885FNTB 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.