Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MPG | P29372 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929832 | 0.90 | CA12 (0.49) | CYP1A2DHFRKCNH2MEN1KMT2A | |
| SCHEMBL19929827 | 0.88 | KDM4E (0.51) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19934851 | 0.83 | KDM4E (0.51) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19929824 | 0.82 | APP (0.56) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19929831 | 0.82 | MEN1 (0.51) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19929830 | 0.79 | MIF (0.46) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19929835 | 0.76 | CYP3A4 (0.50) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19934849 | 0.76 | CYP3A4 (0.50) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL19929829 | 0.75 | MEN1 (0.64) | CYP1A2MEN1KMT2APOLHHSP90AA1 | |
| SCHEMBL29732709 | 0.74 | CYP3A4 (0.57) | CYP1A2MEN1KMT2APOLHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-12-17 | — | — | US | disclosed |
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065945-A1 | SYNTHESIS OF NOVEL ANALOGS OF DIPTOINDONESIN G, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HPGDS, DPP7, DPEP1 | CYP1A2 1976/4885DHFR 532/4885KCNH2 3411/4885 |
| US-10508092-B2 | Synthesis of novel analogs of diptoindonesin G, compounds formed thereby, and pharmaceutical compositions containing them | HPGDS, DPP7, DPEP1 | CYP1A2 1976/4885DHFR 532/4885KCNH2 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.