Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987424 | 0.78 | HPGD (0.61) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL3731573 | 0.76 | HPGD (0.59) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL19936438 | 0.75 | HPGD (0.49) | HPGDALDH1A1USP2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL21379766 | 0.75 | LMNA (0.57) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL1934947 | 0.74 | HPGD (0.55) | HPGDALDH1A1USP2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL21379758 | 0.73 | HPGD (0.55) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL2182275 | 0.71 | HPGD (0.63) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL27798296 | 0.71 | HPGD (0.63) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL14453332 | 0.70 | HPGD (0.61) | HPGDALDH1A1USP2GAAMEN1 | |
| SCHEMBL10777394 | 0.70 | ALDH1A1 (0.67) | HPGDALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045071-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | AGIOS PHARMACEUTICALS, INC. (US) | 2018-03-08 | — | — | WO | disclosed |