Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564719 | 0.81 | HPGD (0.66) | HPGDKMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL12489727 | 0.79 | HPGD (0.62) | HPGDKMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL14453332 | 0.78 | HPGD (0.61) | HPGDKMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL19936404 | 0.78 | HPGD (0.52) | HPGDKMT2AMEN1CYP2C9ALDH1A1 | |
| SCHEMBL243236 | 0.76 | HPGD (1.00) | HPGDALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL1927946 | 0.76 | HPGD (1.00) | HPGDALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL8919062 | 0.76 | HPGD (1.00) | HPGDALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL27929296 | 0.76 | HPGD (1.00) | HPGDALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL436090 | 0.76 | HPGD (1.00) | HPGDALDH1A1USP2LMNAMAPK1 | |
| SCHEMBL5177018 | 0.76 | HPGD (0.58) | HPGDKMT2AMEN1CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050546-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC MATERIAL | Université de Liège (BE) | 2018-03-22 | — | — | WO | disclosed |
| EP-3296292-A1 | METHOD FOR THE PREPARATION OF ALKYL PHENIDATES | Université de Liège (BE) | 2018-03-21 | — | — | EP | disclosed |