Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TXN | P10599 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937141 | 0.77 | MAPT (0.46) | ALDH1A1KDM4EMAPTMAPK1POLB | |
| SCHEMBL2491027 | 0.74 | KDM4E (0.53) | ALDH1A1KDM4EMAPTMAPK1POLB | |
| Ammonia Solution, Strong SCHEMBL28585108 | 0.72 | KDM4E (0.52) | ALDH1A1KDM4EMAPTMAPK1POLB | |
| SCHEMBL19841674 | 0.70 | NPC1 (0.34) | ALDH1A1KDM4EMAPTHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL28608867 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4EMAPTMAPK1POLB | |
| SCHEMBL29853858 | 0.70 | CYP1A2 (0.41) | ALDH1A1KDM4EMAPTHSD17B10TP53 | |
| SCHEMBL4645832 | 0.70 | CYP1A2 (0.41) | ALDH1A1KDM4EMAPTHSD17B10TP53 | |
| SCHEMBL27851831 | 0.70 | KDM4E (0.54) | ALDH1A1KDM4EMAPTHSD17B10NQO2 | |
| SCHEMBL19817098 | 0.69 | HDAC6 (0.41) | ALDH1A1KDM4EMAPTMAPK1HSD17B10 | |
| SCHEMBL22342230 | 0.69 | MAPT (0.37) | ALDH1A1KDM4EMAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200255478-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | ALMIRALL SA (ES) | 2020-08-13 | — | — | US | disclosed |
| WO-2019030298-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | ALMIRALL, S.A. (ES) | 2019-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255478-A1 | NOVEL COMPOUNDS ACTIVATING THE NRF2 PATHWAY | KEAP1, NFE2L2, HMOX1 | ALDH1A1 2164/4885KDM4E 4679/4885MAPT 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.