Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | FAP | Q12884 | 3/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14023952 | 1.00 | DPP4 (0.36) | DPP4MCHR1DPP8DPP9FAP | |
| SCHEMBL19063266 | 0.78 | ALDH1A1 (0.46) | L3MBTL1 | |
| SCHEMBL14024029 | 0.78 | SLC6A4 (0.33) | DPP4DPP8DPP9FAPSLC6A4 | |
| SCHEMBL14025104 | 0.77 | ACACB (0.43) | L3MBTL1 | |
| SCHEMBL19062611 | 0.76 | ADRB1 (0.46) | DPP4 | |
| SCHEMBL14025098 | 0.76 | ADRB1 (0.46) | DPP4 | |
| SCHEMBL14023963 | 0.74 | DPP4 (0.37) | DPP4DPP8DPP9DPP7NOTUM | |
| SCHEMBL19937334 | 0.74 | DPP4 (0.44) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL14025103 | 0.73 | KDM4E (0.45) | DPP4DPP7 | |
| SCHEMBL19302976 | 0.72 | MAPT (0.52) | NOTUML3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |