Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937334 | 0.83 | DPP4 (0.44) | DPP4DPP7KCNH2DPP8DPP9 | |
| SCHEMBL15628549 | 0.80 | DPP4 (0.35) | DPP4DPP7ACACB | |
| SCHEMBL15628606 | 0.80 | DPP4 (0.35) | DPP4DPP7ACACB | |
| SCHEMBL14025094 | 0.78 | GSK3B (0.41) | RORCHIF1A | |
| SCHEMBL14024886 | 0.77 | ADRB1 (0.44) | — | |
| SCHEMBL14025102 | 0.75 | KDM4E (0.47) | DPP4RORC | |
| SCHEMBL14023957 | 0.74 | DPP4 (0.36) | DPP4DPP7NOTUMDPP8DPP9 | |
| SCHEMBL14023952 | 0.74 | DPP4 (0.36) | DPP4DPP7NOTUMDPP8DPP9 | |
| SCHEMBL25017269 | 0.72 | HRH3 (0.45) | DPP4DPP7NOTUMACACB | |
| SCHEMBL25016625 | 0.72 | HRH3 (0.45) | DPP4DPP7NOTUMACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008143729-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |