Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565452 | 0.64 | NPSR1 (0.49) | KDM4ENPSR1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL19939402 | 0.64 | PIK3CG (0.41) | KDM4EALDH1A1LMNATP53AHR | |
| SCHEMBL19194488 | 0.64 | TP53 (0.40) | KDM4ENPSR1POLBALDH1A1LMNA | |
| SCHEMBL4577346 | 0.63 | — | — | |
| SCHEMBL6261617 | 0.62 | ALDH1A1 (0.45) | ALDH1A1LMNATP53AHRMAPK1 | |
| SCHEMBL4613719 | 0.62 | L3MBTL1 (0.46) | ALDH1A1LMNATP53AHRMAPK1 | |
| SCHEMBL9504134 | 0.62 | TP53 (0.36) | KDM4ENPSR1POLBALDH1A1LMNA | |
| SCHEMBL19942355 | 0.62 | — | — | |
| SCHEMBL11916281 | 0.61 | ADORA3 (0.36) | ALDH1A1LMNATP53AHRMAPK1 | |
| SCHEMBL18792209 | 0.61 | HTT (0.33) | KDM4EALDH1A1LMNATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065971-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065971-A1 | sGC STIMULATORS | GUCY1A2, PRKG1, GMPS | KDM4E 3250/4885NPSR1 1760/4885POLB 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.