SCHEMBL1994016

SCHEMBL1994016

CC(C)(O)C(C)(C)OB(O)c1cc(F)c(F)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036925 0.88 VRK1 (0.33)
SCHEMBL9938339 0.86
SCHEMBL15525340 0.83 RIPK1 (0.31)
SCHEMBL18579909 0.82
SCHEMBL18580703 0.82
SCHEMBL17112790 0.80 HSD17B1 (0.34)
SCHEMBL18706327 0.79
SCHEMBL486017 0.79 ALDH1A1 (0.35)
SCHEMBL18580552 0.77 TRIM24 (0.30)
SCHEMBL16734984 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486916-B Synthesis method of 3,4, 5-trifluoro-phenylboronic acid 山东国邦药业有限公司 2024-04-12 CN claimed
CN-117486916-A Synthesis method of 3,4, 5-trifluoro-phenylboronic acid 山东国邦药业有限公司 2024-02-02 CN claimed
EP-4522606-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS Merck Sharp & Dohme LLC (US) 2025-03-19 EP disclosed
CN-117486916-B Synthesis method of 3,4, 5-trifluoro-phenylboronic acid 山东国邦药业有限公司 2024-04-12 CN disclosed
CN-117486916-A Synthesis method of 3,4, 5-trifluoro-phenylboronic acid 山东国邦药业有限公司 2024-02-02 CN disclosed
WO-2023220223-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS MERCK SHARP & DOHME LLC (US) 2023-11-16 WO disclosed
US-20230365531-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS MERCK SHARP & DOHME LLC (US) 2023-11-16 US disclosed
CN-116444499-A Phenylalanine derivative containing 4-quinazolinone and preparation method and application thereof 山东大学 2023-07-18 CN disclosed
US-8637710-B2 Catalyst for cross-coupling reaction comprising unsubstituted or substituted bisphosphinobenzenes KYOTO UNIVERSITY (JP) 2014-01-28 US disclosed
US-20110152523-A1 CATALYST FOR CROSS-COUPLING REACTION, AND PROCESS FOR PRODUCTION OF AROMATIC COMPOUND USING THE SAME KYOTO UNIVERSITY (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365531-A1 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMO VIRUS METAP1, SARS1, RTF1 MEN1 1635/4885KMT2A 3118/4885
US-20110152523-A1 CATALYST FOR CROSS-COUPLING REACTION, AND PROCESS FOR PRODUCTION OF AROMATIC COMPOUND USING THE SAME AHR, AR, HRH2 MEN1 452/4885KMT2A 1095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.