Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945534 | 0.85 | TDP1 (0.60) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL8945290 | 0.84 | TDP1 (0.58) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL6596814 | 0.82 | JMJD6 (0.49) | JMJD6KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL6596817 | 0.82 | JMJD6 (0.49) | JMJD6KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL27525131 | 0.81 | PKM (0.59) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL8945285 | 0.79 | KDM5A (0.56) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL12486679 | 0.79 | TDP1 (0.58) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL19921398 | 0.78 | JMJD6 (0.52) | JMJD6TDP1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL20963391 | 0.77 | KDM4E (0.55) | JMJD6KMT2ALMNARAB9ASMN1; SMN2 | |
| SCHEMBL30745058 | 0.77 | KDM4E (0.55) | JMJD6KMT2ALMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290412-A1 | HIV-1 NUCLEOCAPSID INHIBITORS | Università degli Studi di Siena (IT) | 2018-03-07 | — | — | EP | disclosed |