Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.56 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KDM6B | O15054 | 1/20 | 0.56 |
| ▸ | TET3 | O43151 | 1/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM5C | P41229 | 1/20 | 0.56 |
| ▸ | ASPH | Q12797 | 1/20 | 0.56 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.56 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.56 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.56 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.56 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945534 | 0.93 | TDP1 (0.60) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL8945290 | 0.88 | TDP1 (0.58) | KDM5AKDM4CKDM5BALDH1A1ALKBH5 | |
| SCHEMBL27525131 | 0.85 | PKM (0.59) | KDM4CKDM5BALDH1A1KDM4EKDM6B | |
| SCHEMBL24359749 | 0.82 | L3MBTL1 (0.52) | ALDH1A1MAPTKMT2ATDP1SLC6A2 | |
| SCHEMBL25591895 | 0.82 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EEGLN1KMT2ATDP1 | |
| SCHEMBL18607390 | 0.82 | PKM (0.52) | ALDH1A1MAPTKMT2ATDP1SLC6A2 | |
| SCHEMBL24414106 | 0.82 | TDP1 (0.50) | ALDH1A1KDM4EMAPTEGLN1KMT2A | |
| SCHEMBL13637123 | 0.81 | TDP1 (0.49) | ALDH1A1EGLN1KMT2ATDP1SLC6A2 | |
| SCHEMBL1920448 | 0.80 | FTO (0.61) | KDM5AKDM4CKDM5BALDH1A1ALKBH5 | |
| SCHEMBL24360100 | 0.80 | PKM (0.53) | ALDH1A1KDM4EMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409119-B1 | N,N'-Bis(alkoxy-alkyl)-pyridine-2,4-dicarboxylic acid amides, process for their preparation as well as their use | HOECHST AG (DE) | 1994-04-13 | — | — | EP | claimed |
| US-5519038-A | ENZYME INHIBITORS SUITABLE AS FIBROSUPPRESSANTS AND IMMUNOSUPPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |
| CN-1060655-A | 4-or 5-substituted pyridines-2-carboxylic acid, their preparation method and medicinal | HOECHST AG (DE) | 1992-04-29 | — | — | CN | disclosed |