Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260744 | 0.78 | HCAR2 (0.48) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL2338040 | 0.73 | GAA (0.39) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL28815661 | 0.73 | GAA (0.39) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL12393899 | 0.73 | NR1I2 (0.45) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL12003317 | 0.72 | GLA (0.39) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL27260468 | 0.70 | ALDH1A1 (0.41) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL11601388 | 0.69 | GLA (0.41) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL9772247 | 0.69 | GAA (0.36) | L3MBTL1MGAMGAASIMGAM2 | |
| SCHEMBL1147121 | 0.69 | — | — | |
| SCHEMBL10974526 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290514-A1 | APPLICATION OF PI4KIII PROTEIN AND RELATED MEMBRANE PROTEIN COMPLEX IN TREATING ALZHEIMER'S DISEASE | Jiangsu Nuo-Beta Pharmaceutical Technology Co., Ltd. (CN) | 2018-03-07 | — | — | EP | disclosed |