Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23106949 | 0.86 | ALDH1A1 (0.40) | ALDH1A1POLBL3MBTL1KMT2ARECQL | |
| SCHEMBL3781306 | 0.85 | POLB (0.35) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7663419 | 0.85 | POLB (0.35) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10485411 | 0.69 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1KMT2ARECQL | |
| SCHEMBL7360243 | 0.69 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1KMT2ARECQL | |
| SCHEMBL1218407 | 0.69 | ALDH1A1 (0.41) | ALDH1A1POLBL3MBTL1KMT2ARECQL | |
| SCHEMBL13515251 | 0.68 | KDM4E (0.35) | TDP1 | |
| SCHEMBL10029224 | 0.65 | TDP1 (0.48) | ALDH1A1POLBL3MBTL1KMT2AAPEX1 | |
| SCHEMBL21117867 | 0.65 | TDP1 (0.48) | ALDH1A1POLBL3MBTL1KMT2AAPEX1 | |
| SCHEMBL351863 | 0.65 | TDP1 (0.48) | ALDH1A1POLBL3MBTL1KMT2AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041091-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-03-08 | — | — | WO | disclosed |