Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.43 |
| ▸ | CTSL | P07711 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13471019 | 0.92 | CASP3 (0.46) | SYKCTSSCTSLCTSBBCHE | |
| SCHEMBL8722981 | 0.84 | CTSK (0.53) | PSMB5CTSKSYKPSMB8PSMB9 | |
| SCHEMBL30999385 | 0.84 | CTSK (0.53) | PSMB5CTSKSYKPSMB8PSMB9 | |
| SCHEMBL31360618 | 0.84 | CTSK (0.43) | PSMB5CTSKSYKCTSSCTSL | |
| SCHEMBL29813236 | 0.83 | CTSK (0.53) | PSMB5CTSKSYKPSMB8PSMB9 | |
| SCHEMBL19944839 | 0.83 | NMBR (0.59) | CTSKCTSSCTSL | |
| SCHEMBL30999344 | 0.82 | PSMB5 (0.51) | PSMB5CTSKSYKCTSSCTSL | |
| SCHEMBL19944560 | 0.81 | ECE1 (0.50) | PSMB5CTSKSYKCTSB | |
| SCHEMBL31119164 | 0.81 | REN (0.55) | PSMB5CTSKSYKCTSSCTSL | |
| SCHEMBL7887054 | 0.81 | CASP3 (0.51) | PSMB5CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |