Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015896 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL19015751 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2CTSK | |
| SCHEMBL19944837 | 0.69 | PSMB5 (0.46) | CTSSCTSK | |
| SCHEMBL20356179 | 0.69 | MEN1 (0.43) | CTSS | |
| SCHEMBL30565182 | 0.68 | MEN1 (0.42) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL13471245 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2CTSK | |
| SCHEMBL13471019 | 0.68 | CASP3 (0.46) | CTSS | |
| SCHEMBL646203 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL645609 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL13139840 | 0.68 | SMN1; SMN2 (0.50) | SMN1; SMN2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697246-B1 | SELECTIVE CYSTEINE PROTEASE INHIBITORS AND USES THEREOF | GENESIS TECH LIMITED (BB) | 2018-03-07 | — | — | EP | disclosed |