Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12514988 | 0.99 | TSHR (0.46) | TSHRLNPEPERAP2SSTR3ROCK2 | |
| SCHEMBL19445896 | 0.95 | TSHR (0.49) | TSHRLNPEPERAP2SSTR3ROCK2 | |
| SCHEMBL12515011 | 0.94 | TSHR (0.50) | TSHRLNPEPERAP2SSTR3ROCK2 | |
| SCHEMBL21371961 | 0.90 | TSHR (0.43) | TSHRSSTR3FPR2LTA4HFFAR1 | |
| SCHEMBL19944796 | 0.90 | TSHR (0.43) | TSHRSSTR3FPR2LTA4HFFAR1 | |
| SCHEMBL21371614 | 0.90 | ERAP2 (0.42) | TSHRLNPEPERAP2LTA4HERAP1 | |
| SCHEMBL19219773 | 0.90 | ERAP2 (0.42) | TSHRLNPEPERAP2LTA4HERAP1 | |
| SCHEMBL21371982 | 0.90 | ERAP2 (0.42) | TSHRLNPEPERAP2LTA4HERAP1 | |
| SCHEMBL13977371 | 0.90 | TSHR (0.45) | TSHRLNPEPERAP2SSTR3ROCK2 | |
| SCHEMBL12514974 | 0.89 | TSHR (0.44) | TSHRSSTR3FPR2LTA4HFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10206894-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | POLYMEDIX, INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206894-B2 | Compounds for use in treatment of mucositis | MUC1, FUT6, SI | TSHR 4769/4885LNPEP 802/4885ERAP2 692/4885 |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | MUC1, FUT6, SI | TSHR 4769/4885LNPEP 802/4885ERAP2 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.