Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21371961 | 1.00 | TSHR (0.43) | TSHRPTPN1HDAC3HDAC4HDAC1 | |
| SCHEMBL12514974 | 0.99 | TSHR (0.44) | TSHRPTPN1HDAC3HDAC4HDAC1 | |
| SCHEMBL21372024 | 0.94 | TSHR (0.47) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12515010 | 0.94 | TSHR (0.48) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21372022 | 0.91 | HDAC1 (0.44) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12514985 | 0.91 | MMP2 (0.43) | TSHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL19945192 | 0.90 | TSHR (0.45) | TSHRPTPN1FFAR1LTA4HSSTR3 | |
| SCHEMBL12514988 | 0.89 | TSHR (0.46) | TSHRPTPN1FFAR1LTA4HSSTR3 | |
| SCHEMBL21371982 | 0.89 | ERAP2 (0.42) | TSHRFFAR1ITGB3ITGA2BLTA4H | |
| SCHEMBL21371614 | 0.89 | ERAP2 (0.42) | TSHRFFAR1ITGB3ITGA2BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10206894-B2 | Compounds for use in treatment of mucositis | INNOVATION PHARMACEUTICALS INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | POLYMEDIX, INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10206894-B2 | Compounds for use in treatment of mucositis | MUC1, FUT6, SI | TSHR 4769/4885PTPN1 3664/4885HDAC3 291/4885 |
| US-20180064664-A1 | Compounds For Use In Treatment of Mucositis | MUC1, FUT6, SI | TSHR 4769/4885PTPN1 3664/4885HDAC3 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.